{"id":696,"date":"2018-02-25T12:43:54","date_gmt":"2018-02-25T12:43:54","guid":{"rendered":"http:\/\/cru.aeu.es\/?p=696"},"modified":"2018-02-25T12:43:54","modified_gmt":"2018-02-25T12:43:54","slug":"ingenieria-tisular-en-hipospadia","status":"publish","type":"post","link":"https:\/\/cru.aeu.es\/?p=696","title":{"rendered":"Ingenieria tisular en hipospadia"},"content":{"rendered":"
Front Pediatr.<\/a><\/span>\u00a02018 Jan 22;5:283.<\/div>\n

Current Status of Tissue Engineering in the Management of Severe\u00a0Hypospadias<\/span>.<\/h1>\n
Abbas TO<\/a>1,<\/sup>2,<\/sup>3<\/sup>,\u00a0Mahdi E<\/a>4<\/sup>,\u00a0Hasan A<\/a>4<\/sup>,\u00a0AlAnsari A<\/a>5<\/sup>,\u00a0Pennisi CP<\/a>1<\/sup><\/div>\n
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<\/div>\n<\/div>\n
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Abstract<\/h3>\n
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Hypospadias<\/span>, characterized by misplacement of the urinary meatus in the lower side of the penis, is a frequent birth defect in male children. Because of the huge variation in the anatomic presentation of\u00a0hypospadias<\/span>, no single urethroplasty procedure is suitable for all situations. Hence, many\u00a0surgical<\/span>\u00a0techniques have emerged to address the shortage of tissues required to bridge the gap in the urethra particularly in the severe forms of\u00a0hypospadias<\/span>. However, the rate of postoperative complications of currently available\u00a0surgical<\/span>\u00a0procedures<\/span>\u00a0reaches up to one-fourth of the patients having severe\u00a0hypospadias<\/span>. Moreover, these urethroplasty techniques are technically demanding and require considerable\u00a0surgical<\/span>\u00a0experience. These limitations have fueled the development of novel tissue engineering techniques that aim to simplify the\u00a0surgical<\/span>\u00a0procedures<\/span>\u00a0and to reduce the rate of complications. Several types of biomaterials have been considered for urethral repair, including synthetic and natural polymers, which in some cases have been seeded with cells prior to implantation. These methods have been tested in preclinical and clinical studies, with variable degrees of success. This review describes the different urethral tissue engineering methodologies, with focus on the approaches used for the treatment of\u00a0hypospadias<\/span>. At present, despite many significant advances, the search for a suitable tissue engineering approach for use in routine clinical applications continues.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Front Pediatr.\u00a02018 Jan 22;5:283. Current Status of Tissue Engineering in the Management of Severe\u00a0Hypospadias. Abbas TO1,2,3,\u00a0Mahdi E4,\u00a0Hasan A4,\u00a0AlAnsari A5,\u00a0Pennisi CP1 Abstract Hypospadias, characterized by misplacement of the urinary meatus in the lower side of the penis, is a frequent birth …<\/p>\n

Ingenieria tisular en hipospadia<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,10],"tags":[],"class_list":["post-696","post","type-post","status-publish","format-standard","hentry","category-bibliografiainteres","category-hipospadia-infantil"],"_links":{"self":[{"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/posts\/696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=696"}],"version-history":[{"count":1,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/posts\/696\/revisions"}],"predecessor-version":[{"id":697,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/posts\/696\/revisions\/697"}],"wp:attachment":[{"href":"https:\/\/cru.aeu.es\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=696"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=696"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}