{"id":639,"date":"2017-11-18T07:33:19","date_gmt":"2017-11-18T07:33:19","guid":{"rendered":"http:\/\/cru.aeu.es\/?p=639"},"modified":"2017-11-18T07:33:19","modified_gmt":"2017-11-18T07:33:19","slug":"reparacion-de-hipospadia-y-desarrollo-de-estenosis-en-adulto-correlacion","status":"publish","type":"post","link":"https:\/\/cru.aeu.es\/?p=639","title":{"rendered":"Reparaci\u00f3n de hipospadia y desarrollo de estenosis en adulto: correlaci\u00f3n"},"content":{"rendered":"
Eur Urol Focus.<\/a><\/span>\u00a02017 Apr;3(2-3):287-292. doi: 10.1016\/j.euf.2017.02.005. Epub 2017 Feb 21.<\/div>\n

Correlation Between Primary\u00a0Hypospadias<\/span>\u00a0Repair and Subsequent Urethral Strictures in a Series of 408 Adult Patients.<\/h2>\n
Barbagli G<\/a>1<\/sup>,\u00a0Fossati N<\/a>2<\/sup>,\u00a0Larcher A<\/a>2<\/sup>,\u00a0Montorsi F<\/a>2<\/sup>,\u00a0Sansalone S<\/a>3<\/sup>,\u00a0Butnaru D<\/a>4<\/sup>,\u00a0Lazzeri M<\/a>5<\/sup>.<\/div>\n
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<\/div>\n<\/div>\n
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Abstract<\/h3>\n
\n

BACKGROUND:<\/h4>\n

The correlation between primary\u00a0hypospadias<\/span>\u00a0repair and subsequent urethral strictures in adults has never been addressed.<\/p>\n

OBJECTIVE:<\/h4>\n

To evaluate the correlation between the site of primary\u00a0hypospadias<\/span>\u00a0repair and the site of subsequent strictures and to investigate the predictive factors of failure after urethroplasty.<\/p>\n

DESIGN, SETTING, AND PARTICIPANTS:<\/h4>\n

An observational, retrospective, descriptive study of adult patients with urethral strictures following\u00a0hypospadias<\/span>\u00a0surgery was carried out in a single centre.<\/p>\n

INTERVENTION:<\/h4>\n

Meatotomy, meatoplasty, end-to-end anastomosis, urethroplasty, perineostomy, urethrotomy, and fistula closure.<\/p>\n

OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS:<\/h4>\n

We performed correlations between the site of primary\u00a0hypospadias<\/span>\u00a0and the site of subsequent strictures, treatment failure, and patient lack of motivation for definitive treatment. Cross-tables, Kaplan-Meier curves, and logistic or Cox regression were used.<\/p>\n

RESULTS AND LIMITATIONS:<\/h4>\n

A total of 408 patients, with median follow-up of 96 mo, were included. Concordance between the site of primary\u00a0hypospadias<\/span>\u00a0repair and the site of subsequent strictures was observed. Multivariable analysis revealed that the number of previous operations needed for initial\u00a0hypospadias<\/span>\u00a0repair was not associated with the risk of treatment failure (hazard ratio [HR] 0.96; 95% confidence Interval [CI] 0.88-1.04; p=0.3) or a lack of patient motivation (odds ratio 0.99, 95% CI 0.90-1.10; p=0.9). Length of stenosis (HR 1.38, 95% CI 1.11-1.71; p=0.004) and lichen sclerosus (HR 1.73, 95% CI 1.03-3.25; p=0.035) were associated with a higher risk of treatment failure. Our study is not representative of the entire population of patients with\u00a0hypospadias<\/span>\u00a0repair.<\/p>\n

CONCLUSIONS:<\/h4>\n

The stricture site is usually consistent with the site of\u00a0hypospadias<\/span>. Stricture length, but not the number of previous operations needed for primary\u00a0hypospadias<\/span>\u00a0repair, was associated with the risk of failure.<\/p>\n

PATIENT SUMMARY:<\/h4>\n

The number of operations needed for\u00a0hypospadias<\/span>\u00a0repair was not associated with failure of subsequent urethroplasty.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Eur Urol Focus.\u00a02017 Apr;3(2-3):287-292. doi: 10.1016\/j.euf.2017.02.005. Epub 2017 Feb 21. Correlation Between Primary\u00a0Hypospadias\u00a0Repair and Subsequent Urethral Strictures in a Series of 408 Adult Patients. Barbagli G1,\u00a0Fossati N2,\u00a0Larcher A2,\u00a0Montorsi F2,\u00a0Sansalone S3,\u00a0Butnaru D4,\u00a0Lazzeri M5. Abstract BACKGROUND: The correlation between primary\u00a0hypospadias\u00a0repair and subsequent …<\/p>\n

Reparaci\u00f3n de hipospadia y desarrollo de estenosis en adulto: correlaci\u00f3n<\/span> Leer m\u00e1s \u00bb<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-639","post","type-post","status-publish","format-standard","hentry","category-adulto-uretra"],"_links":{"self":[{"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/posts\/639","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=639"}],"version-history":[{"count":1,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/posts\/639\/revisions"}],"predecessor-version":[{"id":640,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=\/wp\/v2\/posts\/639\/revisions\/640"}],"wp:attachment":[{"href":"https:\/\/cru.aeu.es\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=639"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=639"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cru.aeu.es\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=639"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}